He was the nephew of Joseph the Betrothed, and one of the Seventy. When the Apostle James, first Bishop of Jerusalem, was martyred, St Symeon was named to replace him. As second Bishop of Jerusalem he governed the Church there to a very great age. In the time of the Emperor Trajan a persecution broke out in Palestine against both Christians and Jews; Symeon was condemned on both counts, and was privileged to die, like his Lord, by crucifixion. He was 120 years old.