The son of peasants, he was known from his childhood for his piety and asceticism. Once, by his prayers, a spring of water sprang up near his village, where it was needed for the town's survival. When he came of age, Polychronius went to work in some vineyards near Constantinople. Even though he labored all day, he would eat only every two or three days. The master of the vineyard, seeing his strict and prayerful way of life, gave him a large sum of money and said 'Man of God, go home and pray for me.' With the money, Polychronius built a church, settled near it, and a few years later was ordained to be a priest in the church he had built. Polychronius appeared at the First Ecumenical Council in 325 as a fervent defender of Orthodoxy. Because of this, some Arian heretics determined to take revenge. One day, after the death of the Emperor Constantine, the Arians attacked Polychronius at the altar as he was celebrating the Divine Liturgy, thus mingling his blood with the very blood of the Savior.